Menotropins (GMH 150 IU HMG) 150 IU contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women.
Menotropins is used as a fertility medication that is injected either subcutaneously or intramuscularly.
Drug = Menotropins
Strength = 150 IU
Manufacturer = Sun Pharma
Quantity per sleeve = 1 Vial (for the price quoted)
How To Take Menotropins (GMH 150 IU HMG) 150 IU
Take GMH 150 IU Injection as instructed by the doctor. It is advised to take this medicine under the supervision of your doctor or a trained healthcare professional. Appropriate diagnostic tests must be performed before starting the treatment therapy with this medicine. You should take this medicine under the supervision of a doctor who is appropriately qualified and experienced.
Dosage of Menotropins (GMH 150 IU HMG) 150 IU
Female Infertility: Daily dose providing 75-150 units FSH. Adjust dose gradually till adequate response. Once reached, stop menotrophin and induce ovulation with chorionic gonadotrophin 1-2 days later. In menstruating patients, start treatment within the 1st 7 days of the menstrual cycle; may repeat the cycle at least twice more if needed.
In vitro fertilisation procedures or other assisted conception techniques: As monotherapy or with clomiphene citrate or gonadorelin agonist: Daily dose providing 75-300 units FSH, usually started on the 2nd or 3rd of the menstrual cycle and continued till adequate response is obtained, followed by chorionic gonadotrophin 1-2 days after the last menotrophin injection only if there are less than 3 follicles, less than 17 mm in diameter with 17-β-estradiol levels equal or less than 3,500 pmol/L.
Male infertility: with chorionic gonadotropin: Daily dose providing 75 or 150 units FSH 2-3 times weekly, continue treatment for 3-4 months.
Missed Dose of Menotropins (GMH 150 IU HMG) 150 IU
If you often forget to take your medicine, let your doctor and pharmacist know.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.
Do not double a dose under any circumstances.
Overdose
Signs of overdose may include the following:
- Ovarian hyperstimulation
Seek medical help immediately.
Contraindications of Menotropins (GMH 150 IU HMG) 150 IU
People with the following medical conditions should not take Menotropins:
- Pregnancy
- Lactation
- Ovarian cysts or enlarged ovaries
- Uncontrolled thyroid
- Adrenal dysfunction
- Organic intracranial lesions
- Abnormal genital bleeding of unknown cause
- Presence of other causes of infertility other than ovulation
- Hormone sensitive tumors
- Primary ovarian failure
- Malformation of sexual organs or fibroid tumors of the uterus incompatible with pregnancy
- Tubal occlusion
- Ovarian dysgenesis
- Absent uterus or premature menopause
Side Effects of Menotropins (GMH 150 IU HMG) 150 IU
Menotropins may have the following side effects:
- Ovarian enlargement
- Ovarian cysts
- Enlarged abdomen
- Gastrointestinal disturbances
- Injection site reactions
- Headache
- Dizziness
- Tachycardia
- Dyspnea
- Tachypnea
- Hypersensitivity reactions
- Multiple births
- Miscarriages
Potentially Fatal:
- Ovarian hyperstimulation syndrome
- Atelectasis
- Acute respiratory distress syndrome
- Thromboembolic events
Warnings of Menotropins (GMH 150 IU HMG) 150 IU
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Menotropins.
How Does It Work?
Menotropins effectiveness is mainly due to its Follicle Stimulating Hormone content. In the ovaries, the FSH-component increases the quantity of growing follicles and stimulates their development, thus under the influence of Luteinizing Hormone, FSH increases estradiol production in the granulosa cells. In the testes, FSH induces the maturation of Sertoli cells and the seminal canals and the development of the spermatozoa.
Uses
Menotropins is used to treat the following conditions:
- Female infertility
- In vitro fertilisation procedures or other assisted conception techniques
- Male infertility
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
In females:
- Monitor ovarian activity and measure urinary estrogen at regular intervals, until stimulation occurs.
- Refrain from sexual intercourse or use barrier contraception methods for at least 4 days and pelvic examinations to be avoided or carried out with care.
Storage Conditions
- Store ≤25°C. Protect from light.
- Store in a cool, dry place away from the reach of children.
- Do not use Menotropin that is expired or out of expiry date.
