Sildenafil + Dapoxetine is a combination treatment for erectile dysfunction and premature ejaculation. This medication contains the active ingredients Sildenafil Citrate and Dapoxetine. Patients can have more solid erections and more command over the length of intercourse with this drug.
This medicine is made up of two medications commonly used in the treatment of premature ejaculation.Sildenafil works by inhibiting a particular type 5 phosphodiesterase, which is located primarily in the penis corpus cavernosum, resulting in extended penile erection. Dapoxetine works by inhibiting the serotonin transporter resulting in increased serotonin production in both presynaptic and postsynaptic receptors, thus greatly decreasing premature ejaculation.
Drug = Sildenafil + Dapoxetine
Strength = 100/60 mg
Manufacturer = Sunrise
Quantity per sleeve = 10 Tablet (for the price quoted)
How To Take Sildenafil + Dapoxetine (Malegra DXT Plus) 100/60mg Tabs
Take this medication exactly as prescribed by the doctor. Follow all the usage instructions mentioned on the label. Do not take in larger or smaller quantities than prescribed. It is recommended to have regular follow up with the doctor while taking this medicine.
Always take this medicine with a large glass of water. Avoid large or fatty meals close to when you intend to take medicine.
This medicine will become effective within 30 to 60 minutes. Effective treatment time is 4 – 6 hours.
Dosage of Sildenafil + Dapoxetine (Malegra DXT Plus) 100/60mg Tabs
The safe indicated dose within 24 hours is one tablet of Sildenafil Citrate/Dapoxetine.
Missed Dose of Sildenafil + Dapoxetine (Malegra DXT Plus) 100/60mg Tabs
If you often forget to take your medicine, let your doctor and pharmacist know.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.
Do not double a dose under any circumstances.
Overdose
If you think you may have used Sildenafil + Dapoxetine more than the usual dose, please seek medical help immediately.
Contraindications
People with the following medical conditions should not take Sildenafil + Dapoxetine:
- Aortic stenosis
- Idiopathic hypertrophic subaortic stenosis
- General ventricular outflow obstruction
- Stroke
- Myocardial infarction (heart attack)
- Serious arrhythmia
- Unstable angina
- Patients with severely impaired autonomic control of blood pressure
- Resting hypotension (low blood pressure) of (BP <90/50)
- Resting hypertension (high blood pressure) of (BP >170/110)
- Retinitis pigmentosa (genetic disease of the retina)
- Sickle cell or other related anemias
- HIV (specifically on treatment with protease inhibitors)
- Organ donor recipients
- Depression
Side Effects
Sildenafil + Dapoxetine may have the following side effects:
- Dizziness
- Lightheadedness
- Nervousness
- Confusion
- Excessive sweating
- Headache
- Diarrhea
- Sleeplessness
- Decreased libido
- Blurred vision
- Ringing or buzzing in the ears
- Fast/irregular heartbeat
- Increase in blood pressure
- Excessive tiredness
- Dry mouth
Warnings
Do not take Sildenafil + Dapoxetine with the following medicines:
- Nitroglycerin medicines
- Nitroprusside medicines
- Amyl Nitrate
- Organ Donor Recipient medicines
- Azole antifungal
- Selective Serotonin Reuptake Inhibitors
- Serotonin Norepinephrine Reuptake Inhibitors
- Lithium
- Tricyclic antidepressants
- Monoamine Oxidase Inhibitors
- L-Tryptophans
- Triptans
- Tramadol
- Linezolid
- St John’s Wort
- CYP3A4 inhibitors
- HIV protease inhibitors
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements, and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Sildenafil + Dapoxetine.
How Does It Work?
This medication is a combination of two drugs explicitly used for the treatment of premature ejaculation in men aged between 18 and 64 years. Sildenafil acts by inhibiting a specific phosphodiesterase type 5 enzyme, which is found mainly in the corpus cavernosum of the penis, thereby leading to prolonged and sustained penile erection. Dapoxetine acts by inhibiting the serotonin transporter, leading to an increased serotonin activity at the presynaptic and postsynaptic receptors, thereby reducing premature ejaculation significantly.
Uses
Sildenafil + Dapoxetine is used to treat the following conditions:
- Premature ejaculation
- Erectile dysfunction
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Pregnancy
- Lactation
- Use in healthy men
- Orthostatic hypotension
- Use in children
- Bleeding disorders
- Seizures
- Lactose intolerance
- Dizziness and fainting
Storage Conditions
- Store in a cool, dry place away from the reach of children.
- Do not use Sildenafil + Dapoxetine that is expired or out of date.
