Chorionic Gonadotropin (Pregnyl-Ovunal SC 5000) is a polypeptide hormone produced by the human placenta which interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy.
It secretes the hormone progesterone during the first trimester, which is required for maintenance of the uterus and prevents menstruation. In males, it also stimulates the production of gonadal steroid hormones by stimulating the interstitial cells of the testes to produce androgens.
Drug = Chorionic Gonadotropin
Strength = 5000 IU
Manufacturer = Intas
Quantity per sleeve = 1 Vial (for the price quoted)
How To Take Chorionic Gonadotropin (Pregnyl-Ovunal SC 5000)
HCG is given as an injection under the skin or into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
Use HCG exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Dosage of Chorionic Gonadotropin (Pregnyl-Ovunal SC 5000)
Male infertility due to hypogonadotropic hypogonadism: 500-1,000 units 2-3 times/week.
Delayed puberty due to hypogonadism in males: 1,500 units twice weekly for at least 6 months.
Anovulatory infertility: 5,000-10,000 units as a single dose. May repeat inj (up to 5,000 u/inj) up to 3 times within the next 9 days.
Missed Dose of Chorionic Gonadotropin (Pregnyl-Ovunal SC 5000)
If you often forget to take your medicine, let your doctor and pharmacist know.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.
Do not double a dose under any circumstances.
Overdose of Chorionic Gonadotropin (Pregnyl-Ovunal SC 5000)
If you think you may have used Human Chorionic Gonadotropin more than the usual dose, please seek medical help immediately.
Contraindications
People with the following medical conditions should not take Human Chorionic Gonadotropin:
- Hypersensitivity
- Precocious puberty
- Prostatic carcinoma
- Androgenic dependent neoplasm
- Pregnancy
- Lactation
Side Effects
Chorionic Gonadotropin may have the following side effects:
- Headache
- Irritability
- Restlessness
- Depression
- Fatigue
- Edema
- Precocious puberty
- Gynecomastia
- Pain at Injection site
- Enlargement of preexisting ovarian cysts and possible rupture
- Arterial thromboembolism
- Shock
- Abdominal pain
- Ovarian hyperstimulation syndrome (OHSS)
Warnings
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Human Chorionic Gonadotropin.
How Does It Work?
Chorionic Gonadotropin is a polypeptide hormone produced by the human placenta which works by stimulating the gonadal steroid hormones production by inducing interstitial cells of the testes to produce androgens and the corpus luteum of the ovary to produce progesterone.
Uses
Chorionic Gonadotropin is used to treat the following conditions:
- Male infertility due to hypogonadotropic hypogonadism
- Delayed puberty due to hypogonadism in males
- Anovulatory infertility
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Discontinue therapy if signs of precocious puberty are seen in patients treated for cryptorchidism
- Patients with cardiac or renal disease
- Epilepsy
- Migraine
- Asthma
Storage Conditions
- Vials of the product should be stored between 2°C – 8°C. Do not freeze. Keep protected from light.
- Use the reconstituted solution immediately after preparation; any unused portion should be discarded.
- Store in a cool, dry place away from the reach of children.
