Emtricitabine-Tenofovir(Truvada-Tenvir)EM 200-300mg is a nucleoside reverse transcriptase inhibitor used together with other medicines to treat Human Immunodeficiency virus (HIV) infection.
Emtricitabine works by inhibiting the HIV reverse transcriptase, thereby preventing the transcription of HIV RNA to DNA.
Drug = Emtricitabine-Tenofovir
Strength = 200/300 mg
Manufacturer = Cipla
Quantity per sleeve = 30 Tabs (for the price quoted)
How To Take Emtricitabine-Tenofovir(Truvada-Tenvir)EM 200-300mg
This medicine may be taken with or without food. Try to take it at the same time each day.
This medicine is available as a capsule or as an oral solution.
Emtricitabine must be taken regularly for it to be effective. Do not stop taking it unless instructed by your doctor.
Take Emtricitabine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Emtricitabine-Tenofovir(Truvada-Tenvir)EM 200-300mg
HIV-1 infection: A tablet containing 200 mg of emtricitabine and 300 mg of tenofovir : 1 tablet once daily. For patients with swallowing difficulties, tablets may be disintegrated in approx 100 ml of water, orange juice or grape juice and consumed immediately.
Missed Dose of Emtricitabine-Tenofovir(Truvada-Tenvir)EM 200-300mg
If you often forget to take your medicine, let your doctor and pharmacist know.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.
Do not double a dose under any circumstances.
Overdose of Emtricitabine-Tenofovir(Truvada-Tenvir)EM 200-300mg
If you think you may have used Emtricitabine/Tenofovir more than the usual dose, please seek medical help immediately.
Contraindications
People with the following medical conditions should not take Emtricitabine/Tenofovir :
- Hypersensitivity
Side Effects
Emtricitabine/Tenofovir may have the following side effects:
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Dyspepsia
- Flatulence
- Pain
- Hypersensitivity,
- Increased pigmentation
- Asthenia
- Osteonecrosis
- Osteomalacia
- Hyperglycemia
- Insulin resistance
- Hypercholesterolemia
- Hypertriglyceridemia
- Hyperlactatemia
- Lipodystrophy
- Elevated lipase, amylase, creatine kinase or transaminases levels
- Hyperbilirubinemia
- Insomnia
- Abnormal dreams
- Neutropenia
- Anemia
- Immune reactivation syndrome
- Renal impairment
- Acute renal failure
- Fanconi syndrome.
Potentially Fatal:
- Lactic acidosis
- Severe hepatomegaly with steatosis
Warnings of
Inform your doctor and pharmacist if you are taking the following:
- Ribavirin
- Lamivudine
- Valganciclovir
- Ganciclovir
- Orlistat
- Cladribine
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Emtricitabine/Tenofovir
How Does It Work?
Tenofovir is a diester prodrug of tenofovir, which is rapidly converted to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analogue of adenosine 5′-monophosphate while emtricitabine is a synthetic nucleoside analogue of cytidine. Both emtricitabine and tenofovir work by inhibiting HIV-1 reverse transcriptase, resulting in DNA chain termination.
Uses
Emtricitabine/Tenofovir is used to treat the following conditions:
- HIV Infection
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Patient with severe immune deficiency
- Chronic hepatitis B
- Renal impairment
- Children
- Pregnancy
- Lactation
- Avoid alcohol
Storage Conditions
- Store between 15-30°C (59-86°F).
- Store in a cool, dry place away from the reach of children.
- Do not use Emtricitabine/Tenofovir that is expired or out of expiry date.
